Abbreviations

  • 1,25(OH)2D: 1,25-dihydroxyvitamin D
  • 6MWT: 6-minute walk test
  • 25(OH)D: 25-hydroxyvitamin D
  • ALP: alkaline phosphatase
  • BLA: biologics license application
  • CI: confidence interval
  • CMA: conditional marketing authorisation
  • EMA: European Medicines Agency
  • FDA: Food and Drug Administration
  • FGF23: fibroblast growth factor 23
  • GEE: generalized estimating equation
  • GLMM: generalized linear mixed model
  • LS mean: least squares mean
  • MAA: marketing authorisation application
  • PHEX: phosphate-regulating endopeptidase homolog on the X chromosome
  • PTH: parathyroid hormone
  • Q2W: every two weeks
  • RGI-C: radiographic global impression of change
  • ROW: rest of the world
  • RSS: rickets severity score
  • SC: subcutaneous
  • SD: standard deviation
  • TEAEs: treatment-emergent adverse events
  • TmP/GFR: ratio of the renal tubular maximum reabsorption rate of phosphate (TmP) to glomerular filtration rate (GFR).
  • XLH: X-linked hypophosphataemia

This websites uses cookies to give you the best browsing experience. By clicking Accept you agree to the use of cookies on this site. For more details about how we use cookes visit the Cookies page.